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NTB-A/SLAMF6 Polyclonal antibody, PBS Only

NTB-A/SLAMF6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 22711-1-PBS

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Synonyms

验证数据展示

  • IHC staining of human colon cancer using 22711-1-AP (same clone as 22711-1-PBS)

    IHC staining of human colon cancer using 22711-1-AP (same clone as 22711-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22711-1-AP (SLAMF6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22711-1-PBS in a different storage buffer formulation.

  • WB analysis of Daudi using 22711-1-AP (same clone as 22711-1-PBS)

    WB analysis of Daudi using 22711-1-AP (same clone as 22711-1-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 22711-1-AP (SLAMF6 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22711-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 22711-1-AP (same clone as 22711-1-PBS)

    IHC staining of human colon cancer using 22711-1-AP (same clone as 22711-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22711-1-AP (SLAMF6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22711-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 22711-1-AP (same clone as 22711-1-PBS)

    IHC staining of human tonsillitis using 22711-1-AP (same clone as 22711-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22711-1-AP (SLAMF6 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22711-1-PBS in a different storage buffer formulation.

产品信息

22711-1-PBS targets NTB-A/SLAMF6 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen NTB-A/SLAMF6 fusion protein Ag18517 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name SLAM family member 6
Synonyms
Calculated Molecular Weight 332 aa, 37 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC114495
Gene Symbol SLAMF6
Gene ID (NCBI) 114836
RRIDAB_2879154
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96DU3
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Signaling lymphocyte activation molecule 6 (SLAMF6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules (PMID:31199820). SLAMF6 is a type I transmembrane protein with two extracellular immunoglobins (Ig)-like domains and three cytoplasmic tyrosine-based signaling motifs, one of which is immunoreceptor tyrosine-based switch motif (PMID:31315913). SLAMF6 is expressed on a wide variety of immune cells including T cells (also TFH), B cells, NK cells (expressed in humans only), double positive thymocytes, eosinophils, and neutrophils (mouse only) (PMID:11862385).