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Neurotrophin 4 Polyclonal antibody

Neurotrophin 4 Polyclonal Antibody for WB, IF/ICC, ELISA
Cat No. 12297-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, ELISA and More (3)

NTF4, NT-4, NT4, NT 4, Neutrophic factor 4

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive WB detected inA431 cells, mouse brain tissue, rat brain tissue, rat cerebellum tissue, rat kidney tissue
Positive IF/ICC detected inPC-3 cells, SH-SY5Y cells
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:3000
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

12297-1-AP targets Neurotrophin 4 in WB, IHC, IF/ICC, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, ELISA Application Description
文献引用应用WB, IHC, CoIP, IF
经测试反应性 human, mouse, rat
文献引用反应性human
免疫原 Neurotrophin 4 fusion protein Ag2938 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 neurotrophin 4
别名 NTF4, NT-4, NT4, NT 4, Neutrophic factor 4
计算分子量 210 aa, 22 kDa
观测分子量70-80 kDa
GenBank蛋白编号BC012421
基因名称 Neurotrophin 4
Gene ID (NCBI) 4909
RRIDAB_10598309
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP34130
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Neurotrophin 4 (NT-4) belongs to the family of neurotrophic factors, and it interacts with the tyrosine kinase B (trkB) receptor. NT-4 has neuroprotective effects following cerebral ischemia. Its role might be similar to brain-derived neurotrophic factor (BDNF) because both interact with trkB. Exercise also improves neural function by increasing neurotrophic factors. NT-4 exists in two forms, either as a dimer (80 kDa) or as a monomer (40-47 kDa) (PMID: 23526925).

实验方案

Product Specific Protocols
WB protocol for Neurotrophin 4 antibody 12297-1-APDownload protocol
IF protocol for Neurotrophin 4 antibody 12297-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,IHC,IF,CoIP

Int J Oncol

Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.

Authors - Zhou Yang
  • KD Validated
humanWB

Onco Targets Ther

Analysis of risk factors for colon cancer progression.

Authors - Zhou Yang
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