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NTRK1 Monoclonal antibody

NTRK1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

3B11C7

Cat no : 60548-1-Ig

Print datasheet

Synonyms

TRK1, Trk A, TRK, p140 TrkA, MTC

验证数据展示

  • WB analysis using 60548-1-Ig

    WB analysis using 60548-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

  • WB analysis of NK-92 using 60548-1-Ig

    WB analysis of NK-92 using 60548-1-Ig

    NK-92 cells were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

  • WB analysis using 60548-1-Ig

    WB analysis using 60548-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inKarpas-299 cells, NK-92 cells, SH-SY5Y cells, IMR-32 cells, TF-1 cells, K-562 cells, MOLT-4 cells, SK-N-SH cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

60548-1-Ig targets NTRK1 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen NTRK1 fusion protein Ag27985 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name neurotrophic tyrosine kinase, receptor, type 1
Synonyms TRK1, Trk A, TRK, p140 TrkA, MTC
Calculated Molecular Weight 88 kDa
Observed Molecular Weight140 kDa
GenBank Accession NumberNM_001007792
Gene Symbol NTRK1
Gene ID (NCBI) 4914
RRIDAB_3670266
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP04629
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

NTRK1(Neurotrophic tyrosine kinase receptor 1) is located on chromosome 1q23.1 and is responsible for a rare genetic disorder, CIPA (congenital insensitivity to pain with anhidrosis) (PMID: 37907480). As a neurotrophin receptor, NTRK1 is abundantly expressed in human neuronal tissues and plays an integral role in the development and function of the human nervous system (PMID: 27843590). NTRK1 also regulates the survival and proliferation of cholinergic neurons (PMID: 20054812).

实验方案

Product Specific Protocols
WB protocol for NTRK1 antibody 60548-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols