TrkA Monoclonal antibody, PBS Only

TrkA Monoclonal Antibody for WB, Indirect ELISA
Cat No. 60548-1-PBS

产品说明书

CloneNo. 3B11C7

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, Indirect ELISA

NTRK1, Trk A, TRK, p140 TrkA, MTC

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

60548-1-PBS targets TrkA in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 TrkA fusion protein Ag27985 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 neurotrophic tyrosine kinase, receptor, type 1
别名 NTRK1, Trk A, TRK, p140 TrkA, MTC
计算分子量 88 kDa
观测分子量140 kDa
GenBank蛋白编号NM_001007792
基因名称 NTRK1
Gene ID (NCBI) 4914
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP04629
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NTRK1(Neurotrophic tyrosine kinase receptor 1) is located on chromosome 1q23.1 and is responsible for a rare genetic disorder, CIPA (congenital insensitivity to pain with anhidrosis) (PMID: 37907480). As a neurotrophin receptor, NTRK1 is abundantly expressed in human neuronal tissues and plays an integral role in the development and function of the human nervous system (PMID: 27843590). NTRK1 also regulates the survival and proliferation of cholinergic neurons (PMID: 20054812).

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