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NTRK1 Monoclonal antibody, PBS Only

NTRK1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3B11C7

Cat no : 60548-1-PBS

Print datasheet

Synonyms

TRK1, Trk A, TRK, p140 TrkA, MTC

验证数据展示

  • WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

    WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

  • WB analysis of NK-92 using 60548-1-Ig (same clone as 60548-1-PBS)

    WB analysis of NK-92 using 60548-1-Ig (same clone as 60548-1-PBS)

    NK-92 cells were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

  • WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

    WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

产品信息

60548-1-PBS targets NTRK1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen NTRK1 fusion protein Ag27985 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name neurotrophic tyrosine kinase, receptor, type 1
Synonyms TRK1, Trk A, TRK, p140 TrkA, MTC
Calculated Molecular Weight 88 kDa
Observed Molecular Weight140 kDa
GenBank Accession NumberNM_001007792
Gene Symbol NTRK1
Gene ID (NCBI) 4914
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP04629
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NTRK1(Neurotrophic tyrosine kinase receptor 1) is located on chromosome 1q23.1 and is responsible for a rare genetic disorder, CIPA (congenital insensitivity to pain with anhidrosis) (PMID: 37907480). As a neurotrophin receptor, NTRK1 is abundantly expressed in human neuronal tissues and plays an integral role in the development and function of the human nervous system (PMID: 27843590). NTRK1 also regulates the survival and proliferation of cholinergic neurons (PMID: 20054812).