验证数据展示
产品信息
98210-1-PBS targets Neuropilin 1/CD304 in FC applications and shows reactivity with human samples.
| Tested Applications | FC Application Description |
| Tested Reactivity | human |
| Immunogen | Recombinant protein 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | neuropilin 1 |
| Synonyms | neuropilin 1, NRP1, Neuropilin-1, CD304, BDCA4 |
| GenBank Accession Number | BC007533 |
| Gene Symbol | Neuropilin 1 |
| Gene ID (NCBI) | 8829 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | O14786 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Neuropilin 1 (NRP1), also known as CD304 or VEGF165R, is a type I transmembrane proteins consisting of a small intracellular cytoplasmic domain, a transmembrane domain and an extracellular domain containing a complement-binding CUB domain (a1/a2), a coagulation factor V/VIII (b1/b2) domain, and a meprin or MAM domain (PMID: 24263240; 11886873). It is expressed on plasmacytoid dendritic cells (pDCs), endothelial cells, thymocytes, regulatory T cells, a subset of T follicular helper cells, neurons, and diverse human solid tumors (PMID: 31944572; 14991591; 18704117). Neuropilin 1 is involved in immunity, cardiovascular development, neuronal guidance, cell migration, angiogenesis and cancer pathogenesis (PMID: 24263240).