• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

OGDHL Recombinant antibody, PBS Only

OGDHL Recombinant Antibody for IF, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

IF, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

230228B2

Cat No : 82981-1-PBS

Print datasheet

Synonyms

KIAA1290, OGDC E1 like, OGDHL

验证数据展示

  • IF Staining of U2OS using 82981-1-RR (same clone as 82981-1-PBS)

    IF Staining of U2OS using 82981-1-RR (same clone as 82981-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using OGDHL antibody (82981-1-RR, Clone: 230228B2 ) at dilution of 1:300 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 82981-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 82981-1-RR (same clone as 82981-1-PBS)

    IHC staining of human liver using 82981-1-RR (same clone as 82981-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 82981-1-RR (OGDHL antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 82981-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 82981-1-RR (same clone as 82981-1-PBS)

    IHC staining of human liver using 82981-1-RR (same clone as 82981-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 82981-1-RR (OGDHL antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 82981-1-PBS in a different storage buffer formulation.

  • Affinity experiments of 82981-1-RR

    Affinity experiments of 82981-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82981-1-RR against Human OGDHL were performed. The affinity constant is 4.98 nM.

产品信息

82981-1-PBS targets OGDHL in IF, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications IF, IHC, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen OGDHL fusion protein Ag10794 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name oxoglutarate dehydrogenase-like
Synonyms KIAA1290, OGDC E1 like, OGDHL
Calculated Molecular Weight 1010 aa, 115 kDa
GenBank Accession NumberBC026320
Gene Symbol OGDHL
Gene ID (NCBI) 55753
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9ULD0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

OGDHL(oxoglutarate dehydrogenase-like) is also named as KGDE1KL, FLJ10851, KIAA1290 and belongs to the alpha-ketoglutarate dehydrogenase family. OGDHL is one of the rate-limiting component of the multienzyme OGDH complex (OGDHC) whose malfunction is associated with neuro-degeneration and it is localized only in the mitochondrial fraction and not in the cytosolic or nuclear fractions(PMID:23152800). OGDHL negatively regulates cell proliferation by inducing apoptosis in cervical cancer cells. It may thus participate in brain-specific control of 2-oxoglutarate distribution between energy production and synthesis of the neurotransmitter glutamate(PMID:18783430). It has 3 isoforms(114 kDa, 108 kDa, 91 kDa) produced by alternative splicing.