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  • Featured Product
  • KD/KO Validated

OTUD4 Polyclonal antibody, PBS Only

OTUD4 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 25070-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 25070-1-AP (same clone as 25070-1-PBS)

    WB analysis using 25070-1-AP (same clone as 25070-1-PBS)

    Various lysate were subjected to SDS PAGE followed by western blot with 25070-1-AP (OTUD4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25070-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 25070-1-AP (same clone as 25070-1-PBS)

    IHC staining of human kidney using 25070-1-AP (same clone as 25070-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 25070-1-AP (OTUD4 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25070-1-PBS in a different storage buffer formulation.

产品信息

25070-1-PBS targets OTUD4 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen OTUD4 fusion protein Ag18401 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name OTU domain containing 4
Synonyms
Calculated Molecular Weight 1113 aa, 124 kDa
Observed Molecular Weight 140-150 kDa
GenBank Accession NumberBC118653
Gene Symbol OTUD4
Gene ID (NCBI) 54726
RRIDAB_2879882
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ01804
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

OTUD4, a member of the OTU family, encodes for a protein of 495 amino acids with an OTU domain and functions via their enzymatic deubiquitinating activities. OTUD4 nominally encodes a K48-specific deubiquitinase previously shown to counteract proteasomal degradation of DNA repair proteins. OTUD4 has been identified to be down-regulated in multiple human tumor types, and lower OTUD4 expression indicates a poor prognosis.(PMID: 36411454,PMID: 32184655,PMID: 29395066)