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PACSIN2 Recombinant antibody, PBS Only

PACSIN2 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242193H3

Cat no : 84763-4-PBS

Print datasheet

Synonyms

Syndapin-II, Syndapin-2, SdpII, Protein kinase C and casein kinase substrate in neurons protein 2, 242193H3

验证数据展示

  • WB analysis using 84763-4-RR (same clone as 84763-4-PBS)

    WB analysis using 84763-4-RR (same clone as 84763-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84763-4-RR (PACSIN2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84763-4-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 84763-4-RR (same clone as 84763-4-PBS)

    IF Staining of HepG2 using 84763-4-RR (same clone as 84763-4-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using PACSIN2 antibody (84763-4-RR, Clone: 242193H3 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84763-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84763-4-RR

    Affinity and Kinetic Characterization of 84763-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84763-4-RR against Human PACSIN2 were performed. The affinity constant is 3.72 nM.

产品信息

84763-4-PBS targets PACSIN2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen PACSIN2 fusion protein Ag0809 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name protein kinase C and casein kinase substrate in neurons 2
Synonyms Syndapin-II, Syndapin-2, SdpII, Protein kinase C and casein kinase substrate in neurons protein 2, 242193H3
Calculated Molecular Weight 56 kDa
Observed Molecular Weight60 kDa
GenBank Accession NumberBC008037
Gene Symbol PACSIN2
Gene ID (NCBI) 11252
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ9UNF0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Peripheral membrane proteins of the Bin/amphiphysin/Rvs (BAR) and Fer-CIP4 homology-BAR (F-BAR) family participate in cellular membrane trafficking (PMID: 19549836). PACSIN2 (also known as syndapin-2) is a member of the protein kinase C and casein kinase substrate in neurons (PACSIN) family, which are membrane-binding proteins characterized by an amino-terminal F-BAR domain. PACSIN2 plays a role in intracellular vesicle-mediated transport. It is involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization (PMID: 23129763). PACSIN2 also has a role in caveolae membrane sculpting (PMID: 21610094).