验证数据展示
产品信息
12648-1-PBS targets PDE9A in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | IHC, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | PDE9A fusion protein Ag3372 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | phosphodiesterase 9A |
Synonyms | HSPDE9A2, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, EC:3.1.4.35 |
Calculated Molecular Weight | 68 kDa |
Observed Molecular Weight | 50 kDa |
GenBank Accession Number | BC009047 |
Gene Symbol | PDE9A |
Gene ID (NCBI) | 5152 |
RRID | AB_2161890 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | O76083 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Cyclic nucleotide phosphodiesterases (PDEs), which hydrolyze the intracellular second messengers cAMP and cGMP to their corresponding monophosphates, play an important role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. PDE9A plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. This protein has 16 isoforms with the MW between 44 kDa and 65 kDa.