PDLIM5 Monoclonal antibody, PBS Only
PDLIM5 Monoclonal Antibody for WB,Indirect ELISA
Host / Isotype
Mouse / IgM
Reactivity
Human
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1H9C9
验证数据展示
Mouse monoclonal antibodies of IgM isotype can be detected with "anti-mouse IgG (H+L)" secondary antibodies.
产品信息
67651-1-PBS targets PDLIM5 in WB, Indirect ELISA applications and shows reactivity with Human samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | Human |
Immunogen | PDLIM5 fusion protein Ag25059 种属同源性预测 |
Host / Isotype | Mouse / IgM |
Class | Monoclonal |
Type | Antibody |
Full Name | PDZ and LIM domain 5 |
Synonyms | ENH, ENH1, Enigma homolog, L9, LIM, PDLIM5, PDZ and LIM domain 5, PDZ and LIM domain protein 5 |
Calculated Molecular Weight | 64 kDa |
Observed Molecular Weight | 63-69 kDa |
GenBank Accession Number | BC008741 |
Gene Symbol | PDLIM5 |
Gene ID (NCBI) | 10611 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Euglobulin precipitation |
UNIPROT ID | Q96HC4 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PDLIM5 (PDZ and LIM domain 5), formerly known as enigma homolog (ENH), is a cytoplasmic protein containing PDZ domain and LIM domain at N terminus and C terminus, respectively. PDLIM5 gene generates several splicing variants, EZH1 to EZH4. The long isoform, ENH1, is widely expressed in various tissues including heart, brain, spleen, liver and kidney. In comparison, shorter isoforms that lack the LIM motifs are expressed in cardiac (ENH3) and skeletal muscle (ENH2, ENH3, and ENH4). ENH1 is essential for differentiation of striated muscles through interaction with other proteins. In addition, PDLIM5 is also involved in mood disorders, such as schizophrenia, bipolar disorder, and major depression.