PDLIM5 Monoclonal antibody, PBS Only

PDLIM5 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67651-1-PBS

产品说明书

CloneNo. 1H9C9

宿主/亚型

Mouse / IgM

种属反应性

Human

应用

WB, Indirect ELISA

ENH, ENH1, Enigma homolog, L9, LIM, PDLIM5, PDZ and LIM domain 5, PDZ and LIM domain protein 5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


Mouse monoclonal antibodies of IgM isotype can be detected with "anti-mouse IgG (H+L)" secondary antibodies.

产品信息

67651-1-PBS targets PDLIM5 in WB, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human
免疫原 PDLIM5 fusion protein Ag25059 种属同源性预测
宿主/亚型 Mouse / IgM
抗体类别 Monoclonal
产品类型 Antibody
全称 PDZ and LIM domain 5
别名 ENH, ENH1, Enigma homolog, L9, LIM, PDLIM5, PDZ and LIM domain 5, PDZ and LIM domain protein 5
计算分子量 64 kDa
观测分子量 63-69 kDa
GenBank蛋白编号BC008741
基因名称 PDLIM5
Gene ID (NCBI) 10611
RRIDAB_2882850
偶联类型 Unconjugated
形式 Liquid
纯化方式Euglobulin precipitation
UNIPROT IDQ96HC4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PDLIM5 (PDZ and LIM domain 5), formerly known as enigma homolog (ENH), is a cytoplasmic protein containing PDZ domain and LIM domain at N terminus and C terminus, respectively. PDLIM5 gene generates several splicing variants, EZH1 to EZH4. The long isoform, ENH1, is widely expressed in various tissues including heart, brain, spleen, liver and kidney. In comparison, shorter isoforms that lack the LIM motifs are expressed in cardiac (ENH3) and skeletal muscle (ENH2, ENH3, and ENH4). ENH1 is essential for differentiation of striated muscles through interaction with other proteins. In addition, PDLIM5 is also involved in mood disorders, such as schizophrenia, bipolar disorder, and major depression.

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