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Serpin F1/PEDF Monoclonal antibody, PBS Only

Serpin F1/PEDF Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, pig

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C5C8

Cat no : 66554-1-PBS

Print datasheet

Synonyms

PIG35, PEDF, EPC-1, EPC 1, Cell proliferation-inducing gene 35 protein

验证数据展示

  • WB analysis of human plasma using 66554-1-Ig (same clone as 66554-1-PBS)

    WB analysis of human plasma using 66554-1-Ig (same clone as 66554-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 66554-1-Ig (PEDF antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66554-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy SERPINF1/PEDF Ready-To-Use IHC Kit. SERPINF1/PEDF primary antibody included.

产品信息

66554-1-PBS targets Serpin F1/PEDF in WB, Indirect ELISA applications and shows reactivity with human, pig samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, pig
Immunogen Serpin F1/PEDF fusion protein Ag26660 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Synonyms PIG35, PEDF, EPC-1, EPC 1, Cell proliferation-inducing gene 35 protein
Calculated Molecular Weight 418 aa, 46 kDa
Observed Molecular Weight 46-50 kDa
GenBank Accession NumberBC013984
Gene Symbol PEDF
Gene ID (NCBI) 5176
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP36955
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PEDF also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functionsis. It is an approximately 50-kDa secreted protein that is widely expressed, including by osteoblasts and osteoclasts. PEDF is also one of the most abundant secretory products of adipocytes, and circulating concentrations of PEDF correlate positively with body fat mass and INS resistance. PEDF is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.