验证数据展示
产品信息
68555-1-PBS targets PEX19 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat, pig |
免疫原 | PEX19 fusion protein Ag6858 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | peroxisomal biogenesis factor 19 |
别名 | PMPI, PMP1, PEX, Peroxin-19, OK/SW-cl.22 |
计算分子量 | 33 kDa |
观测分子量 | 35-40 kDa |
GenBank蛋白编号 | BC000496 |
基因名称 | PEX19 |
Gene ID (NCBI) | 5824 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P40855 |
储存缓冲液 | PBS Only |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. PEX19 gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) (PMID: 14709540). PEX19 may bind newly synthesized PMPs and facilitate their insertion into the peroxisome membrane (PMID: 107044440. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14) (PMID:20683989) (PMID:10051604).