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PEX19 Monoclonal antibody, PBS Only

PEX19 Monoclonal Antibody for WB,Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, pig

Applications

WB,Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3H2C2

Cat No : 68555-1-PBS

Print datasheet

Synonyms

33 kDa housekeeping protein, D1S2223E, HK33, Peroxin 19, PEX19, PMP1, PMPI, PXF, PXMP1

验证数据展示

  • WB analysis using 68555-1-Ig (same clone as 68555-1-PBS)

    WB analysis using 68555-1-Ig (same clone as 68555-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68555-1-Ig (PEX19 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68555-1-PBS in a different storage buffer formulation.

产品信息

68555-1-PBS targets PEX19 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Applications WB,Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, pig
Immunogen PEX19 fusion protein Ag6858 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name peroxisomal biogenesis factor 19
Synonyms 33 kDa housekeeping protein, D1S2223E, HK33, Peroxin 19, PEX19, PMP1, PMPI, PXF, PXMP1
Calculated Molecular Weight 33 kDa
Observed Molecular Weight 35-40 kDa
GenBank Accession NumberBC000496
Gene Symbol PEX19
Gene ID (NCBI) 5824
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP40855
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. PEX19 gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) (PMID: 14709540). PEX19 may bind newly synthesized PMPs and facilitate their insertion into the peroxisome membrane (PMID: 107044440. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14) (PMID:20683989) (PMID:10051604).