验证数据展示
产品信息
68385-1-PBS targets PFKL in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Rabbit, Pig samples.
经测试应用 | WB, IHC, IF/ICC, FC (Intra), Indirect ELISA Application Description |
经测试反应性 | Human, Mouse, Rat, Rabbit, Pig |
免疫原 | PFKL fusion protein Ag8250 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | phosphofructokinase, liver |
别名 | PFK B, EC:2.7.1.11, ATP-PFK, ATP-dependent 6-phosphofructokinase, liver type, 6-phosphofructokinase type B |
计算分子量 | 85 kDa |
观测分子量 | 85 kDa |
GenBank蛋白编号 | BC008964 |
基因名称 | PFKL |
Gene ID (NCBI) | 5211 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P17858 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PFKL (6-phosphofructokinase, liver type) is also named as PFK-B and belongs to the phosphofructokinase family. The PFKL gene encodes the liver isoform of phosphofructokinase (PFK) (ATP: D-fructose-6-phosphate-1-phosphotransferase). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. In human beings, PFK exists as a system of three subunits: these are the muscle(PFKM), liver(PFKL), and platelet(PFKP) PFKs (PMID: 2139864). It has 2 isoforms produced by alternative splicing.