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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 82796-4-RR (same clone as 82796-4-PBS)

    WB analysis using 82796-4-RR (same clone as 82796-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82796-4-RR (PIK3CA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82796-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82796-4-RR

    Affinity and Kinetic Characterization of 82796-4-RR

    Biolayer interferometry (BLl) kinetic assays of 82796-4-RR against Human PI3 Kinase p110 Alpha were performed. The affinity constant is 0.639 nM.

PI3 Kinase p110 Alpha Recombinant antibody, PBS Only

PI3 Kinase p110 Alpha Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 82796-4-PBS

产品说明书

CloneNo. 1B4

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

PI3K p110(alpha), PIK3CA, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, p110 alpha

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PIK3CA Ready-To-Use IHC Kit. PIK3CA primary antibody included.

产品信息

82796-4-PBS targets PI3 Kinase p110 Alpha in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 PI3 Kinase p110 Alpha fusion protein Ag16586 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 phosphoinositide-3-kinase, catalytic, alpha polypeptide
别名 PI3K p110(alpha), PIK3CA, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, p110 alpha
计算分子量 1068 aa, 124 kDa
观测分子量110 kDa
GenBank蛋白编号BC113601
基因名称 PIK3CA
Gene ID (NCBI) 5290
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP42336
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB).