PI3 Kinase p110 Alpha Recombinant antibody, PBS Only
PI3 Kinase p110 Alpha Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, mouse, rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1B4
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy PIK3CA Ready-To-Use IHC Kit. PIK3CA primary antibody included.
产品信息
82796-4-PBS targets PI3 Kinase p110 Alpha in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | Human, mouse, rat |
Immunogen | PI3 Kinase p110 Alpha fusion protein Ag16586 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | phosphoinositide-3-kinase, catalytic, alpha polypeptide |
Synonyms | PI3K p110(alpha), PIK3CA, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, p110 alpha |
Calculated Molecular Weight | 1068 aa, 124 kDa |
Observed Molecular Weight | 110 kDa |
GenBank Accession Number | BC113601 |
Gene Symbol | PIK3CA |
Gene ID (NCBI) | 5290 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P42336 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB).