验证数据展示
产品信息
28750-1-PBS targets PLK4 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | PLK4 fusion protein Ag30482 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | polo-like kinase 4 (Drosophila) |
别名 | |
计算分子量 | 970 aa, 109 kDa |
GenBank蛋白编号 | BC036023 |
基因名称 | PLK4 |
Gene ID (NCBI) | 10733 |
RRID | AB_2881206 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | O00444 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PLK4 (Polo-like kinase 4) is also named SAK, STK18 and belongs to the Ser/Thr protein kinase family. It plays a central role in centriole duplication and is a kinase implicated in tumor development, which is an upstream regulator of canonical biogenesis necessary for centriole formation. It has 3 isoforms produced by alternative splicing.