验证数据展示
Mouse monoclonal antibodies of IgA isotype can be detected with "anti-mouse IgG (H+L)" secondary antibodies.
产品信息
66342-1-PBS targets PLOD2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | PLOD2 fusion protein Ag5779 种属同源性预测 |
宿主/亚型 | Mouse / IgA |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
别名 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2, PLOD2/LH2, Lysyl hydroxylase 2, EC:1.14.11.4, 1H9E1 |
计算分子量 | 758 aa, 85 kDa |
观测分子量 | 87 kDa |
GenBank蛋白编号 | BC037169 |
基因名称 | PLOD2 |
Gene ID (NCBI) | 5352 |
RRID | AB_2881722 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | O00469 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PLOD2,also named as LH2, forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. It is a potential novel prognostic factor for HCC patients following surgery. Among the PLOD genes, PLOD2 contributes to cancer prognosis and angiogenesis. Several authors have reported that PLOD2 expression might provide prognostic information about malignant tumours such as glioblastoma. PLOD2 expression is a useful biomarker for the effects of antiangiogenic treatment for malignancy.(PMID:22098155). It has 2 isoforms produced by alternative splicing and seven glycosylation sites.