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验证数据展示

  • WB analysis of MKN-45 using 83449-4-RR (same clone as 83449-4-PBS)

    WB analysis of MKN-45 using 83449-4-RR (same clone as 83449-4-PBS)

    MKN-45 cells were subjected to SDS PAGE followed by western blot with 83449-4-RR (PLXDC2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83449-4-PBS in a different storage buffer formulation.

  • IHC staining of human intrahepatic cholangiocarcinoma using 83449-4-RR (same clone as 83449-4-PBS)

    IHC staining of human intrahepatic cholangiocarcinoma using 83449-4-RR (same clone as 83449-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 83449-4-RR (PLXDC2 antibody) at dilution of 1:800 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83449-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83449-4-RR

    Affinity and Kinetic Characterization of 83449-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83449-4-RR against Human PLXDC2 were performed. The affinity constant is 42.5 pM.

PLXDC2 Recombinant antibody, PBS Only

PLXDC2 Uni-rAbTM Recombinant Antibody for WB, IHC, ELISA
Cat No. 83449-4-PBS

产品说明书

CloneNo. 240174A11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, ELISA

别名

UNQ2514/PRO6003, Tumor endothelial marker 7-related protein, TEM7R, Plexin domain-containing protein 2, plexin domain containing 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

83449-4-PBS targets PLXDC2 in WB, IHC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human
免疫原 PLXDC2 fusion protein Ag2940 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 plexin domain containing 2
别名 UNQ2514/PRO6003, Tumor endothelial marker 7-related protein, TEM7R, Plexin domain-containing protein 2, plexin domain containing 2
计算分子量 480 aa, 54 kDa
观测分子量 54 kDa
GenBank蛋白编号BC012885
基因名称 PLXDC2
Gene ID (NCBI) 84898
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ6UX71
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PLXDC2 (Plexin-domain containing 2), also named tumor endothelial marker 7-related protein (TEM7R), is a single-pass type I membrane protein with some homology to nidogen and to plexins. PLXDC2 is located in tumor endothelium and plays a role in tumor angiogenesis. Three isoforms of PLXDC2 produced by alternative splicing have been described. Recent finding revealed that PLXDC2 is a mitogen for neural progenitors and functions as a novel regulator of the development of different brain regions, suggesting its role in coordinating proliferation and differentiation in the developing nervous system.