验证数据展示
产品信息
14261-1-PBS targets PNPLA6 in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IF/ICC, IP, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | PNPLA6 fusion protein Ag5546 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | patatin-like phospholipase domain containing 6 |
别名 | |
计算分子量 | 150 kDa |
观测分子量 | 150 kDa |
GenBank蛋白编号 | BC051768 |
基因名称 | PNPLA6 |
Gene ID (NCBI) | 10908 |
RRID | AB_2283965 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q8IY17 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PNPLA6(patatin-like phospholipase domain-containing protein 6) is also named as NTE(neuropathy target esterase) and belongs to the NTE family. It plays an important role in motor neuron development and implicated overexpression of BMP signaling(PMID:22996643). Defects in PNPLA6 are the cause of spastic paraplegia autosomal recessive type 39 (SPG39)(PMID:18313024). This protein has a glycosylaion site that it can be glycosylated(PMID:9576844). It has 3 isoforms produced by alternative splicing.