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PNPLA6 Polyclonal antibody, PBS Only

PNPLA6 Polyclonal Antibody for WB, IF/ICC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 14261-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis of HEK-293 using 14261-1-AP (same clone as 14261-1-PBS)

    WB analysis of HEK-293 using 14261-1-AP (same clone as 14261-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 14261-1-AP (PNPLA6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14261-1-PBS in a different storage buffer formulation.

  • IP experiment using 14261-1-AP (same clone as 14261-1-PBS)

    IP experiment using 14261-1-AP (same clone as 14261-1-PBS)

    IP result of anti-PNPLA6 (14261-1-AP for IP and Detection) with HEK-293 cells. This data was developed using the same antibody clone with 14261-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 14261-1-AP (same clone as 14261-1-PBS)

    IF Staining of HepG2 using 14261-1-AP (same clone as 14261-1-PBS)

    Immunofluorescent analysis of HepG2 cells, using PNPLA6 antibody 14261-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). This data was developed using the same antibody clone with 14261-1-PBS in a different storage buffer formulation.

产品信息

14261-1-PBS targets PNPLA6 in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF/ICC, IP, Indirect ELISA Application Description
Tested Reactivity human
Immunogen PNPLA6 fusion protein Ag5546 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name patatin-like phospholipase domain containing 6
Synonyms
Calculated Molecular Weight 150 kDa
Observed Molecular Weight 150 kDa
GenBank Accession NumberBC051768
Gene Symbol PNPLA6
Gene ID (NCBI) 10908
RRIDAB_2283965
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8IY17
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PNPLA6(patatin-like phospholipase domain-containing protein 6) is also named as NTE(neuropathy target esterase) and belongs to the NTE family. It plays an important role in motor neuron development and implicated overexpression of BMP signaling(PMID:22996643). Defects in PNPLA6 are the cause of spastic paraplegia autosomal recessive type 39 (SPG39)(PMID:18313024). This protein has a glycosylaion site that it can be glycosylated(PMID:9576844). It has 3 isoforms produced by alternative splicing.