验证数据展示
产品信息
85096-1-PBS targets PPAT in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | PPAT fusion protein Ag7618 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | phosphoribosyl pyrophosphate amidotransferase |
Synonyms | |
Calculated Molecular Weight | 57 kDa |
Observed Molecular Weight | 57 kDa |
GenBank Accession Number | BC004200 |
Gene Symbol | PPAT |
Gene ID (NCBI) | 5471 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q06203 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PPAT, also known as ATase (amidophosphoribosyltransferase) or GPAT (glutamine phosphoribosylpyrophosphate amidotransferase) is the rate-limiting enzyme in the de novo pathway of purine ribonucleotide synthesis and is regulated by feedback inhibition by AMP and GMP. PPAT expression modulates pyruvate kinase activity, cell proliferation and invasion (PMID: 26140362).