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PPP2CA Monoclonal antibody, PBS Only

PPP2CA Monoclonal Antibody for WB,Indirect ELISA,IHC

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat

Applications

WB,Indirect ELISA,IHC

Conjugate

Unconjugated

CloneNo.

3A6H5

Cat No : 67809-1-PBS

Print datasheet

Synonyms

PP2A alpha, PP2Ac, PP2CA, PPP2CA, Replication protein C, RP C

验证数据展示

  • WB analysis using 67809-1-Ig (same clone as 67809-1-PBS)

    WB analysis using 67809-1-Ig (same clone as 67809-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67809-1-Ig (PPP2CA antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67809-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 67809-1-Ig (same clone as 67809-1-PBS)

    IHC staining of human liver using 67809-1-Ig (same clone as 67809-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 67809-1-Ig (PPP2CA antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67809-1-PBS in a different storage buffer formulation.

产品信息

67809-1-PBS targets PPP2CA in WB, IHC, Indirect ELISA applications and shows reactivity with Human, rat samples.

Tested Applications WB,Indirect ELISA,IHC Application Description
Tested Reactivity Human, rat
Immunogen PPP2CA fusion protein Ag4294 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
Synonyms PP2A alpha, PP2Ac, PP2CA, PPP2CA, Replication protein C, RP C
Calculated Molecular Weight 309 aa, 36 kDa
Observed Molecular Weight33 kDa
GenBank Accession NumberBC031696
Gene Symbol PPP2CA
Gene ID (NCBI) 5515
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP67775
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

PPP2CA, also named as RP-C and PP2A-alpha, belongs to the PPP phosphatase family and PP-1 subfamily. PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2A activity was modestly decreased in AML patients harboring C-KIT/WT.PP2A is a target for C-KIT/TKD and implicated the potential efficacy of therapies targeting PP2A in such AML in future.