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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67809-1-Ig (same clone as 67809-1-PBS)

    WB analysis using 67809-1-Ig (same clone as 67809-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67809-1-Ig (PPP2CA antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67809-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 67809-1-Ig (same clone as 67809-1-PBS)

    IHC staining of human liver using 67809-1-Ig (same clone as 67809-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 67809-1-Ig (PPP2CA antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67809-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PPP2CA antibody included

PPP2CA Monoclonal antibody, PBS Only

PPP2CA Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67809-1-PBS

产品说明书

CloneNo. 3A6H5

宿主/亚型

Mouse / IgG1

种属反应性

Human, rat

应用

WB, IHC, Indirect ELISA

别名

PP2A alpha, PP2Ac, PP2CA, PPP2CA, Replication protein C, RP C

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PPP2CA Ready-To-Use IHC Kit. PPP2CA primary antibody included.

产品信息

67809-1-PBS targets PPP2CA in WB, IHC, Indirect ELISA applications and shows reactivity with Human, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human, rat
免疫原 PPP2CA fusion protein Ag4294 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
别名 PP2A alpha, PP2Ac, PP2CA, PPP2CA, Replication protein C, RP C
计算分子量 309 aa, 36 kDa
观测分子量33 kDa
GenBank蛋白编号BC031696
基因名称 PPP2CA
Gene ID (NCBI) 5515
RRIDAB_2918572
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP67775
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PPP2CA, also named as RP-C and PP2A-alpha, belongs to the PPP phosphatase family and PP-1 subfamily. PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2A activity was modestly decreased in AML patients harboring C-KIT/WT.PP2A is a target for C-KIT/TKD and implicated the potential efficacy of therapies targeting PP2A in such AML in future.