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PPP2CA Recombinant antibody, PBS Only

PPP2CA Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241112B8

Cat no : 84155-5-PBS

Print datasheet

Synonyms

PP2CA, PP2Ac, PP2A-alpha, PP2A alpha, EC:3.1.3.16

验证数据展示

  • WB analysis using 84155-5-RR (same clone as 84155-5-PBS)

    WB analysis using 84155-5-RR (same clone as 84155-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84155-5-RR (PPP2CA antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84155-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84155-5-RR

    Affinity and Kinetic Characterization of 84155-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84155-5-RR against Human PPP2CA were performed. The affinity constant is 13.6 nM.

Planning an IHC experiment? We recommend our IHCeasy PPP2CA Ready-To-Use IHC Kit. PPP2CA primary antibody included.

产品信息

The immunogen of 84155-5-PBS is PPP2CA Fusion Protein expressed in E. coli.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen PPP2CA fusion protein Ag4294 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
Synonyms PP2CA, PP2Ac, PP2A-alpha, PP2A alpha, EC:3.1.3.16
Calculated Molecular Weight 309 aa, 36 kDa
Observed Molecular Weight 36 kDa
GenBank Accession NumberBC031696
Gene Symbol PPP2CA
Gene ID (NCBI) 5515
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP67775
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PPP2CA, also named as RP-C and PP2A-alpha, belongs to the PPP phosphatase family and PP-1 subfamily. PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2A activity was modestly decreased in AML patients harboring C-KIT/WT.PP2A is a target for C-KIT/TKD and implicated the potential efficacy of therapies targeting PP2A in such AML in future.