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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84155-5-RR (same clone as 84155-5-PBS)

    WB analysis using 84155-5-RR (same clone as 84155-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84155-5-RR (PPP2CA antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84155-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84155-5-RR

    Affinity and Kinetic Characterization of 84155-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84155-5-RR against Human PPP2CA were performed. The affinity constant is 13.6 nM.

PPP2CA Recombinant antibody, PBS Only

PPP2CA Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84155-5-PBS

产品说明书

CloneNo. 241112B8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

PP2CA, PP2Ac, PP2A-alpha, PP2A alpha, EC:3.1.3.16

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PPP2CA Ready-To-Use IHC Kit. PPP2CA primary antibody included.

产品信息

84155-5-PBS targets PPP2CA in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 PPP2CA fusion protein Ag4294 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
别名 PP2CA, PP2Ac, PP2A-alpha, PP2A alpha, EC:3.1.3.16
计算分子量 309 aa, 36 kDa
观测分子量 36 kDa
GenBank蛋白编号BC031696
基因名称 PPP2CA
Gene ID (NCBI) 5515
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP67775
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PPP2CA, also named as RP-C and PP2A-alpha, belongs to the PPP phosphatase family and PP-1 subfamily. PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2A activity was modestly decreased in AML patients harboring C-KIT/WT.PP2A is a target for C-KIT/TKD and implicated the potential efficacy of therapies targeting PP2A in such AML in future.