验证数据展示
产品信息
23827-1-PBS targets PRDM10 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | PRDM10 fusion protein Ag20605 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | PR domain containing 10 |
别名 | |
计算分子量 | 1156 aa, 131 kDa |
观测分子量 | 120-150 kDa |
GenBank蛋白编号 | BC112934 |
基因名称 | PRDM10 |
Gene ID (NCBI) | 56980 |
RRID | AB_2879330 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9NQV6 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PRDM10 is a member of PRDM family, which contains a PR(PRDI-BF1 and RIZ homology) domain, and PRDM is also a subgroup of PR/SET transcription factor family for its PR domain is similar to the catalytic motif of the SET domain of histone methyltransferase(HMTase). Thus PRDM is suggested involve in the regulation of genome expression and chromatin remodeling. PRDM10 shares characteristics with the PR/SET faimly and clusters of zinc fingers DNA binding motifs. It's postualated PRDM10 has an essential role in regulating gene expression and tissue differentiation and a gene repressor. It may play a role in the pathogenesis of gangliosidosis.