验证数据展示
产品信息
67751-1-PBS targets PRKAR2A in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human, rat, mouse samples.
经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human, rat, mouse |
免疫原 | PRKAR2A fusion protein Ag29893 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | protein kinase, cAMP-dependent, regulatory, type II, alpha |
别名 | PKR2, PRKAR2, PRKAR2A |
计算分子量 | 43 kDa |
观测分子量 | 50 kDa |
GenBank蛋白编号 | BC002763 |
基因名称 | PRKAR2A |
Gene ID (NCBI) | 5576 |
RRID | AB_2918520 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P13861 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The effects of cAMP in most tissues and cell types are mainly modulated via protein kinase A, a heterotetrameric protein complex consisting of two regulatory and two catalytic subunits. The regulatory subunit of cAMP-dependent protein kinase (PRKAR2A) is one of the regulatory subunits and the gene is located on chromosome region 3p21.3-p21.2. The expression of PRKAR2A is tightly regulated during spermatogenesis, a significant increase in expression of this gene was also found in the human myometrium during pregnancy.