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PROC Polyclonal antibody, PBS Only

PROC Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 25382-1-PBS

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Synonyms

Vitamin K-dependent protein C, Vitamin K dependent protein C, EC:3.4.21.69, Blood coagulation factor XIV, Autoprothrombin IIA

验证数据展示

  • WB analysis of mouse liver using 25382-1-AP (same clone as 25382-1-PBS)

    WB analysis of mouse liver using 25382-1-AP (same clone as 25382-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 25382-1-AP (PROC Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25382-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 25382-1-AP (same clone as 25382-1-PBS)

    IHC staining of human liver using 25382-1-AP (same clone as 25382-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 25382-1-AP (PROC Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 25382-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 25382-1-AP (same clone as 25382-1-PBS)

    IHC staining of human liver using 25382-1-AP (same clone as 25382-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 25382-1-AP (PROC Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 25382-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 25382-1-AP (same clone as 25382-1-PBS)

    IF Staining of HeLa using 25382-1-AP (same clone as 25382-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using PROC antibody (25382-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 25382-1-PBS in a different storage buffer formulation.

产品信息

25382-1-PBS targets PROC in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen PROC fusion protein Ag11328 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name protein C (inactivator of coagulation factors Va and VIIIa)
Synonyms Vitamin K-dependent protein C, Vitamin K dependent protein C, EC:3.4.21.69, Blood coagulation factor XIV, Autoprothrombin IIA
Calculated Molecular Weight 461 aa, 52 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberBC034377
Gene Symbol PROC
Gene ID (NCBI) 5624
RRIDAB_2880052
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP04070
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PROC belongs to the peptidase S1 family. PROC is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (PMID:25618265). It exerts a protective effect on the endothelial cell barrier function (PMID:25651845).