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PSME3 Monoclonal antibody, PBS Only

PSME3 Monoclonal Antibody for WB, IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Rat

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

2A8E8

Cat no : 67629-1-PBS

Print datasheet

Synonyms

Ki, Ki nuclear autoantigen, PA28 gamma, PA28G, PA28gamma, PSME3, REG GAMMA

验证数据展示

  • WB analysis using 67629-1-Ig (same clone as 67629-1-PBS)

    WB analysis using 67629-1-Ig (same clone as 67629-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67629-1-Ig (PSME3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67629-1-PBS in a different storage buffer formulation.

  • WB analysis using 67629-1-Ig (same clone as 67629-1-PBS)

    WB analysis using 67629-1-Ig (same clone as 67629-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67629-1-Ig (PSME3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67629-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 67629-1-Ig (same clone as 67629-1-PBS)

    IHC staining of human liver cancer using 67629-1-Ig (same clone as 67629-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67629-1-Ig (PSME3 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67629-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PSME3 antibody included
  • IHC staining of human liver cancer using 67629-1-Ig (same clone as 67629-1-PBS)

    IHC staining of human liver cancer using 67629-1-Ig (same clone as 67629-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67629-1-Ig (PSME3 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67629-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PSME3 antibody included
Planning an IHC experiment? We recommend our IHCeasy PSME3 Ready-To-Use IHC Kit. PSME3 primary antibody included.

产品信息

67629-1-PBS targets PSME3 in WB, IHC, ELISA applications and shows reactivity with Human, Rat samples.

Tested Applications WB, IHC, ELISA Application Description
Tested Reactivity Human, Rat
Immunogen PSME3 fusion protein Ag6716 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
Synonyms Ki, Ki nuclear autoantigen, PA28 gamma, PA28G, PA28gamma, PSME3, REG GAMMA
Calculated Molecular Weight 30 kDa
Observed Molecular Weight 32 kDa
GenBank Accession NumberBC001423
Gene Symbol PSME3
Gene ID (NCBI) 10197
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP61289
Storage Buffer PBS only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PSME3 gene encodes proteasome activator complex subunit 3, which is also called REG-gamma or PA28-gamma. REG-gamma activates the trypsin-like catalytic subunit of the proteasome thus is a proteasome regulator. MDM2-TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of TP53, may be promoted by REG-gamma resulting in inhibited apoptosis after DNA damage. REG-gamma may also be involved in cell cycle regulation.