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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67629-1-Ig (same clone as 67629-1-PBS)

    WB analysis using 67629-1-Ig (same clone as 67629-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67629-1-Ig (PSME3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67629-1-PBS in a different storage buffer formulation.

  • WB analysis using 67629-1-Ig (same clone as 67629-1-PBS)

    WB analysis using 67629-1-Ig (same clone as 67629-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67629-1-Ig (PSME3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67629-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 67629-1-Ig (same clone as 67629-1-PBS)

    IHC staining of human liver cancer using 67629-1-Ig (same clone as 67629-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67629-1-Ig (PSME3 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67629-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PSME3 antibody included
  • IHC staining of human liver cancer using 67629-1-Ig (same clone as 67629-1-PBS)

    IHC staining of human liver cancer using 67629-1-Ig (same clone as 67629-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67629-1-Ig (PSME3 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67629-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PSME3 antibody included

PSME3 Monoclonal antibody, PBS Only

PSME3 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 67629-1-PBS

产品说明书

CloneNo. 2A8E8

宿主/亚型

Mouse / IgG1

种属反应性

Human, Rat

应用

WB, IHC, ELISA

别名

Ki, Ki nuclear autoantigen, PA28 gamma, PA28G, PA28gamma, PSME3, REG GAMMA

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PSME3 Ready-To-Use IHC Kit. PSME3 primary antibody included.

产品信息

67629-1-PBS targets PSME3 in WB, IHC, ELISA applications and shows reactivity with Human, Rat samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 Human, Rat
免疫原 PSME3 fusion protein Ag6716 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
别名 Ki, Ki nuclear autoantigen, PA28 gamma, PA28G, PA28gamma, PSME3, REG GAMMA
计算分子量 30 kDa
观测分子量 32 kDa
GenBank蛋白编号BC001423
基因名称 PSME3
Gene ID (NCBI) 10197
RRIDAB_2882830
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP61289
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PSME3 gene encodes proteasome activator complex subunit 3, which is also called REG-gamma or PA28-gamma. REG-gamma activates the trypsin-like catalytic subunit of the proteasome thus is a proteasome regulator. MDM2-TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of TP53, may be promoted by REG-gamma resulting in inhibited apoptosis after DNA damage. REG-gamma may also be involved in cell cycle regulation.