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COX-1/Cyclooxygenase-1 Monoclonal antibody, PBS Only

COX-1/Cyclooxygenase-1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F12G7

Cat no : 67346-1-PBS

Print datasheet

Synonyms

PGH1, PTGS1, PGHS-1, EC:1.14.99.1, Cyclooxygenase-1

验证数据展示

  • WB analysis of L02 using 67346-1-Ig (same clone as 67346-1-PBS)

    WB analysis of L02 using 67346-1-Ig (same clone as 67346-1-PBS)

    L02 cells were subjected to SDS PAGE followed by western blot with 67346-1-Ig (PTGS1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67346-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 67346-1-Ig (same clone as 67346-1-PBS)

    IF Staining of HeLa using 67346-1-Ig (same clone as 67346-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using 67346-1-Ig (PTGS1 antibody) at dilution of 1:100 and CoraLite488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67346-1-PBS in a different storage buffer formulation.

产品信息

67346-1-PBS targets COX-1/Cyclooxygenase-1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen COX-1/Cyclooxygenase-1 fusion protein Ag28280 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms PGH1, PTGS1, PGHS-1, EC:1.14.99.1, Cyclooxygenase-1
Calculated Molecular Weight 599 aa, 69 kDa
Observed Molecular Weight 60-72 kDa
GenBank Accession NumberBC029840
Gene Symbol PTGS1
Gene ID (NCBI) 5742
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP23219
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PTGS1(Prostaglandin G/H synthase 1) belongs to the prostaglandin G/H synthase family and catalyzes the conversion of arachidonic acid to prostaglandin H2, which is subsequently metabolized to various biologically active prostaglandins. It is also named as COX1(Cyclooxygenase-1). There is no PTGS1 expression in fetal samples (prostate, seminal vesicles, or ejaculatory ducts), and only minimal expression in adult tissues (PMID: 10999846). PTGS1 has some isoforms with MW of 56-72 kD and PTGS1 can form homodimer.