验证数据展示
产品信息
67141-1-PBS targets PYK2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat, pig |
免疫原 | PYK2 fusion protein Ag11487 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | PTK2B protein tyrosine kinase 2 beta |
别名 | PTK2B, 2A10G5, CADTK, CAK beta, CAKB |
计算分子量 | 1009 aa, 116 kDa |
观测分子量 | 112-115 kDa |
GenBank蛋白编号 | BC042599 |
基因名称 | PTK2B |
Gene ID (NCBI) | 2185 |
RRID | AB_2882440 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q14289 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Proline-rich tyrosine kinase 2 (Pyk2; also known as CAK, RAFTK and CADTK) is a cytoplasmic tyrosine kinase implicated to play a role in several intracellular signaling pathways. It is expressed in many cells and tissues and migrated as a 130 kDa band in Western Blotting analysis. The size of PYK2 is 115 kDa, and it expressed in many cells and tissues and migrated as a 130 kDa band, but several lower molecular weight bands (75 kDa, 80 kDa, and 97 kDa) were seen in Western Blotting analysis, possibly due to proteolytic degradation.