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  • Featured Product
  • KD/KO Validated

PTPIP51 Polyclonal antibody, PBS Only

PTPIP51 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 20641-1-PBS

Print datasheet

Synonyms

FAM82A2, Protein FAM82A2, hucep-10, hRMD-3, hRMD 3

验证数据展示

  • WB analysis using 20641-1-AP (same clone as 20641-1-PBS)

    WB analysis using 20641-1-AP (same clone as 20641-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20641-1-AP (PTPIP51 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin using 20641-1-AP (same clone as 20641-1-PBS)

    IHC staining of human skin using 20641-1-AP (same clone as 20641-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin using 20641-1-AP (PTPIP51 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin using 20641-1-AP (same clone as 20641-1-PBS)

    IHC staining of human skin using 20641-1-AP (same clone as 20641-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin using 20641-1-AP (PTPIP51 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • IP experiment of HEK-293 using 20641-1-AP (same clone as 20641-1-PBS)

    IP experiment of HEK-293 using 20641-1-AP (same clone as 20641-1-PBS)

    IP result of anti-PTPIP51 (IP:20641-1-AP, 4ug; Detection:20641-1-AP 1:1000) with HEK-293 cells lysate 1100ug. This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • IHC staining of human paracancerous of skin cancer using 20641-1-AP (same clone as 20641-1-PBS)

    IHC staining of human paracancerous of skin cancer using 20641-1-AP (same clone as 20641-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human paracancerous of skin cancer slide using 20641-1-AP (PTPIP51 antibody) at dilution of 1:600 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

产品信息

20641-1-PBS targets PTPIP51 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, IP, Indirect ELISA Application Description
Tested Reactivity human
Immunogen PTPIP51 fusion protein Ag14708 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name family with sequence similarity 82, member A2
Synonyms FAM82A2, Protein FAM82A2, hucep-10, hRMD-3, hRMD 3
Calculated Molecular Weight 470 aa, 52 kDa
Observed Molecular Weight 52-60 kDa
GenBank Accession NumberBC008970
Gene Symbol PTPIP51
Gene ID (NCBI) 55177
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96TC7
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Protein tyrosine phosphatase-interacting protein 51 (PTPIP51),also known as RMDN3, is a mitochondrial membrane-anchored protein that interacts with ER membrane-bound VAPB. The VAPB-PTPIP51 interaction impacts on intracellular Ca2+ handling (PMID: 22131369, 28345618). PTPIP51 participates in multiple cellular processes, and dysfunction of PTPIP51 is implicated in diseases such as cancer and neurodegenerative disorders (PMID: 28345618). The known initiation sites in the Ptpip51 gene would lead to molecular protein masses of 52, 38 and 30 kDa (PMID: 18854601,19844996).