• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84976-1-RR (same clone as 84976-1-PBS)

    WB analysis using 84976-1-RR (same clone as 84976-1-PBS)

    Non-treated and pervanadate treated HeLa cells were subjected to SDS PAGE followed by western blot with 84976-1-RR (Phospho-NTRK1 (Tyr496) antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. The membrane was stripped and re-blotted with Vinculin (66305-1-Ig) antibody as a loading control. This data was developed using the same antibody clone with 84976-1-PBS in a different storage buffer formulation.

Phospho-TrkA (Tyr496)/TrkB (Tyr516) Recombinant antibody, PBS Only

Phospho-TrkA (Tyr496)/TrkB (Tyr516) Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84976-1-PBS

产品说明书

CloneNo. 241917B1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

NTRK1, Trk A, TRK, p140 TrkA, MTC

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

84976-1-PBS targets Phospho-TrkA (Tyr496)/TrkB (Tyr516) in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 neurotrophic tyrosine kinase, receptor, type 1
别名 NTRK1, Trk A, TRK, p140 TrkA, MTC
观测分子量140 kDa
GenBank蛋白编号BC062580
基因名称 NTRK1
Gene ID (NCBI) 4914
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP04629
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The tyrosine kinase receptor TrkA (or neurotrophin receptor kinase 1, NTRK1) has been predominately studied for its role during the development of the nervous system. In developing neurons, TrkA activation upon binding of its ligands nerve growth factor (NGF) or neurotrophin-3 (NT-3) results in the stimulation of various tyrosine kinase-induced signaling pathways leading to neuronal outgrowth. (PMID: 32957504) This antibody recognizes the phosphorylation of TrkA at site 496, which is the phosphorylation of the TrkA-I(isoform 2) sequence at site 490.