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Plasminogen Polyclonal antibody, PBS Only

Plasminogen Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17462-1-PBS

Print datasheet

Synonyms

PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin

验证数据展示

  • WB analysis of human blood using 17462-1-AP (same clone as 17462-1-PBS)

    WB analysis of human blood using 17462-1-AP (same clone as 17462-1-PBS)

    human blood were subjected to SDS PAGE followed by western blot with 17462-1-AP (Plasminogen antibody at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17462-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 17462-1-AP (same clone as 17462-1-PBS)

    IF Staining of HepG2 using 17462-1-AP (same clone as 17462-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using 17462-1-AP (Plasminogen antibody) at dilution of 1:50 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 17462-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach using 17462-1-AP (same clone as 17462-1-PBS)

    IHC staining of human stomach using 17462-1-AP (same clone as 17462-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 17462-1-AP (Plasminogen antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17462-1-PBS in a different storage buffer formulation.

产品信息

17462-1-PBS targets Plasminogen in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Plasminogen fusion protein Ag11217 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name plasminogen
Synonyms PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin
Calculated Molecular Weight 810 aa, 91 kDa
Observed Molecular Weight 97 kDa
GenBank Accession NumberBC060513
Gene Symbol Plasminogen
Gene ID (NCBI) 5340
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP00747
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.