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验证数据展示

  • WB analysis of human plasma using 66399-1-Ig (same clone as 66399-1-PBS)

    WB analysis of human plasma using 66399-1-Ig (same clone as 66399-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 66399-1-Ig (PLG Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66399-1-Ig (PLG Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66399-1-Ig (PLG Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 66399-1-Ig (same clone as 66399-1-PBS)

    IF Staining of HepG2 using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using Plasminogen antibody (66399-1-Ig, Clone: 1F6A11 ) at dilution of 1:800 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using Plasminogen antibody (66399-1-Ig, Clone: 1F6A11 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using Plasminogen antibody (66399-1-Ig, Clone: 1F6A11 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

Plasminogen Monoclonal antibody, PBS Only

Plasminogen Monoclonal Antibody for WB, IHC, IF/ICC, IF-P, ELISA
Cat No. 66399-1-PBS

产品说明书

CloneNo. 1F6A11

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, IF/ICC, IF-P, ELISA

别名

PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin, 1F6A11

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66399-1-PBS targets Plasminogen in WB, IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, IF-P, ELISA Application Description
经测试反应性 human
免疫原 Plasminogen fusion protein Ag9938 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 plasminogen
别名 PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin, 1F6A11
计算分子量 810 aa, 91 kDa
观测分子量 105 kDa
GenBank蛋白编号BC060513
基因名称 Plasminogen
Gene ID (NCBI) 5340
RRIDAB_2881773
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP00747
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.