Plasminogen Monoclonal antibody, PBS Only

Plasminogen Monoclonal Antibody for WB, IHC, IF/ICC, IF-P, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IHC, IF/ICC, IF-P, ELISA

Conjugate

Unconjugated

CloneNo.

1F6A11

Cat no : 66399-1-PBS

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Synonyms

PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin, 1F6A11



产品信息

66399-1-PBS targets Plasminogen in WB, IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, IF/ICC, IF-P, ELISA Application Description
Tested Reactivity human
Immunogen Plasminogen fusion protein Ag9938 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name plasminogen
Synonyms PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin, 1F6A11
Calculated Molecular Weight 810 aa, 91 kDa
Observed Molecular Weight 105 kDa
GenBank Accession NumberBC060513
Gene Symbol Plasminogen
Gene ID (NCBI) 5340
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP00747
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.