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Plasminogen Monoclonal antibody, PBS Only

Plasminogen Monoclonal Antibody for WB, IHC, IF/ICC, IF-P, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IHC, IF/ICC, IF-P, ELISA

Conjugate

Unconjugated

CloneNo.

1F6A11

Cat no : 66399-1-PBS

Print datasheet

Synonyms

PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin, 1F6A11

验证数据展示

  • WB analysis of human plasma using 66399-1-Ig (same clone as 66399-1-PBS)

    WB analysis of human plasma using 66399-1-Ig (same clone as 66399-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 66399-1-Ig (PLG Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66399-1-Ig (PLG Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66399-1-Ig (PLG Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using Plasminogen antibody (66399-1-Ig, Clone: 1F6A11 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using Plasminogen antibody (66399-1-Ig, Clone: 1F6A11 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 66399-1-Ig (same clone as 66399-1-PBS)

    IF Staining of HepG2 using 66399-1-Ig (same clone as 66399-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using Plasminogen antibody (66399-1-Ig, Clone: 1F6A11 ) at dilution of 1:1000 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

产品信息

66399-1-PBS targets Plasminogen in WB, IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, IF/ICC, IF-P, ELISA Application Description
Tested Reactivity human
Immunogen Plasminogen fusion protein Ag9938 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name plasminogen
Synonyms PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin, 1F6A11
Calculated Molecular Weight 810 aa, 91 kDa
Observed Molecular Weight 105 kDa
GenBank Accession NumberBC060513
Gene Symbol Plasminogen
Gene ID (NCBI) 5340
RRIDAB_2881773
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP00747
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.