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Prothymosin Alpha Polyclonal antibody, PBS Only

Prothymosin Alpha Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 10480-1-PBS

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Synonyms

验证数据展示

  • IHC staining of human lymphoma using 10480-1-AP (same clone as 10480-1-PBS)

    IHC staining of human lymphoma using 10480-1-AP (same clone as 10480-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:100 (under 25x lens). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

产品信息

10480-1-PBS targets Prothymosin Alpha in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Prothymosin Alpha fusion protein Ag0732 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name prothymosin, alpha
Synonyms
Calculated Molecular Weight 12 kDa
GenBank Accession NumberBC003510
Gene Symbol Prothymosin Alpha/PTMA
Gene ID (NCBI) 5757
RRIDAB_2174388
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP06454
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.