- Featured Product
- KD/KO Validated
CoraLite® Plus 488-conjugated RAB11A/B Polyclonal antibody
RAB11A/B Polyclonal Antibody for IF/ICC
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
验证数据展示
经过测试的应用
Positive IF/ICC detected in | HepG2 cells, U2OS cells |
Planning an IHC experiment? We recommend our IHCeasy RAB11A/B Ready-To-Use IHC Kit. RAB11A/B primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 15903-1-AP
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-15903 targets RAB11A/B in IF/ICC applications and shows reactivity with human, mouse samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | human, mouse |
Immunogen | RAB11A/B fusion protein Ag8742 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | RAB11A, member RAS oncogene family |
Synonyms | Rab 11, RAB11, RAB11A, Ras related protein Rab 11A, YL8 |
Calculated Molecular Weight | 216 aa, 24 kDa |
Observed Molecular Weight | 24 kDa |
GenBank Accession Number | BC013348 |
Gene Symbol | RAB11A |
Gene ID (NCBI) | 8766 |
RRID | AB_2919124 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P62491 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
RAB11 has two isoform genes RAB11A(YL8) and RAB11B(YPT3), and belongs to the small GTPase superfamily and Rab family. It regulates endocytic recycling. RAB11 may exert its functions by interacting with multiple effector proteins in different complexes. It acts as a major regulator of membrane delivery during cytokinesis. RAB11 regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes. This antibody can recognize both RAB11A(24 kDa) and RAB11B(24 kDa).
实验方案
Product Specific Protocols | |
---|---|
IF protocol for CL Plus 488 RAB11A/B antibody CL488-15903 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |