验证数据展示
产品信息
83740-4-PBS targets RAB37 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | RAB37 fusion protein Ag3717 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | RAB37, member RAS oncogene family |
别名 | Ras-related protein Rab-37, Ras related protein Rab 37, 240838D6 |
计算分子量 | 223 aa, 25 kDa |
观测分子量 | 25 kDa |
GenBank蛋白编号 | BC016615 |
基因名称 | RAB37 |
Gene ID (NCBI) | 326624 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q96AX2 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RAB37, as a small GTPase, plays important roles in several cellular processes through intracellular membrane traffic. RAB37 can regulate insulin secretion in β-cells 7 and TNF-α secretion from activated macrophages. In allergic responses, RAB37 regulated mast cell degranulation. RAB37 has been identified to be a tumor suppressor and it regulated exocytosis of several proteins including TIMP metallopeptidase inhibitor 1 (TIMP1), secreted frizzled-related protein-1 (SFRP1) 12, thrombospondin-1 (TSP1), and soluble ST2.