验证数据展示
Planning an IHC experiment? We recommend our IHCeasy RAB3A Ready-To-Use IHC Kit. RAB3A primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 68052-1-Ig
产品信息
CL488-68052 targets RAB3A in applications and shows reactivity with Human, mouse, rat, pig, rabbit, chicken samples.
| 经测试应用 | Application Description |
| 经测试反应性 | Human, mouse, rat, pig, rabbit, chicken |
| 免疫原 | RAB3A fusion protein Ag8148 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | RAB3A, member RAS oncogene family |
| 别名 | RAB3A, Ras related protein Rab 3A |
| 计算分子量 | 25 kDa |
| 观测分子量 | 25 kDa |
| GenBank蛋白编号 | BC011782 |
| 基因名称 | RAB3A |
| Gene ID (NCBI) | 5864 |
| RRID | AB_2923871 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P20336 |
| 储存缓冲液 | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Rab3A is a small G-protein of the Rab family, that is implicated in vesicle fusion and regulated secretion, particularly in neurotransmitter release. Rab3 subfamily small G proteins (Rab3A, Rab3B, Rab3C, and Rab3D) control the regulated exocytosis in neuronal/secretory cells. Rab3A is the most abundant Rab GTPase in brain, where it is associated with synaptic vesicles. Rab3a is believed to modulate secretion efficiency by stimulating vesicle recruitment to sites of exocytosis and/ or by recruiting regulatory molecules to the docking/ fusion machinery.
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 488 RAB3A antibody CL488-68052 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |