验证数据展示
产品信息
66592-1-PBS targets RAF1 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, IHC, IF/ICC, ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | RAF1 fusion protein Ag25423 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | v-raf-1 murine leukemia viral oncogene homolog 1 |
Synonyms | Proto oncogene c RAF, NS5, EC:2.7.11.1, CRAF, c Raf |
Calculated Molecular Weight | 648 aa, 73 kDa |
Observed Molecular Weight | 70-75 kDa |
GenBank Accession Number | BC018119 |
Gene Symbol | RAF1 |
Gene ID (NCBI) | 5894 |
RRID | AB_2881952 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P04049 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Raf-1 proto-oncogene, serine/threonine kinase(RAF1), is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. RAF1 has two isoforms with MW of 73, 75 kDa. RAF1 plays an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.