RAG1 Monoclonal antibody, PBS Only
RAG1 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human, mouse
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3A1A4
验证数据展示
产品信息
68591-1-PBS targets RAG1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | Human, mouse |
| Immunogen | RAG1 fusion protein Ag30192 种属同源性预测 |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | recombination activating gene 1 |
| Synonyms | RAG 1, RAG1, RNF74 |
| Calculated Molecular Weight | 119 kDa |
| Observed Molecular Weight | 110-119 kDa |
| GenBank Accession Number | NM_000448 |
| Gene Symbol | RAG1 |
| Gene ID (NCBI) | 5896 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P15918 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
背景介绍
Recombination-activating gene (RAG) proteins include RAG1 and RAG2, which are crucial for Ig and T lymphocyte receptor (TCR) fragment rearrangement and are responsible for DNA recognition and cleavage at specific sequences. Mutations in RAG1 result in the complete or partial loss of recombinant enzyme activity, in unbalanced variable-diversity-joining (V(D)J) recombination, and in the impairment of T and B lymphocyte development at the early stages.