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验证数据展示

  • WB analysis using 14013-1-AP (same clone as 14013-1-PBS)

    WB analysis using 14013-1-AP (same clone as 14013-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14013-1-AP (RARB antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14013-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse colon using 14013-1-AP (same clone as 14013-1-PBS)

    IHC staining of mouse colon using 14013-1-AP (same clone as 14013-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 14013-1-AP (RARB antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14013-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RARB antibody included
  • IHC staining of mouse colon using 14013-1-AP (same clone as 14013-1-PBS)

    IHC staining of mouse colon using 14013-1-AP (same clone as 14013-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 14013-1-AP (RARB antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14013-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RARB antibody included
  • IF Staining of MCF-7 using 14013-1-AP (same clone as 14013-1-PBS)

    IF Staining of MCF-7 using 14013-1-AP (same clone as 14013-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using RARB antibody (14013-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 14013-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

RARB Polyclonal antibody, PBS Only

RARB Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 14013-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy RARB Ready-To-Use IHC Kit. RARB primary antibody included.

产品信息

14013-1-PBS targets RARB in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 RARB fusion protein Ag5119 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 retinoic acid receptor, beta
别名
计算分子量 50 kDa
观测分子量37-51 kDa
GenBank蛋白编号BC060794
基因名称 RARB
Gene ID (NCBI) 5915
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP10826
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Retinoic acid receptors (RARs) are important mediators of retinoid signaling in morphogenesis, development, and cell differentiation. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes (PMID:12554770). They can bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, they act mainly as activators of gene expression due to weak binding to corepressors. RARB is one isotypes of RARs (PMID:12834868).