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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 11882-1-AP (same clone as 11882-1-PBS)

    WB analysis using 11882-1-AP (same clone as 11882-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11882-1-AP (RBBP6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11882-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 11882-1-AP (same clone as 11882-1-PBS)

    IHC staining of human placenta using 11882-1-AP (same clone as 11882-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11882-1-AP (RBBP6 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11882-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RBBP6 antibody included
  • IHC staining of human rectal cancer using 11882-1-AP (same clone as 11882-1-PBS)

    IHC staining of human rectal cancer using 11882-1-AP (same clone as 11882-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human rectal cancer tissue slide using 11882-1-AP (RBBP6 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11882-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RBBP6 antibody included
  • IHC staining of mouse kidney using 11882-1-AP (same clone as 11882-1-PBS)

    IHC staining of mouse kidney using 11882-1-AP (same clone as 11882-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 11882-1-AP (RBBP6 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11882-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RBBP6 antibody included
  • Featured Product
  • KD/KO Validated

RBBP6 Polyclonal antibody, PBS Only

RBBP6 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11882-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

p53-associated cellular protein of testis, P2PR, P2P R, MY038, EC:2.3.2.27

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy RBBP6 Ready-To-Use IHC Kit. RBBP6 primary antibody included.

产品信息

11882-1-PBS targets RBBP6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen RBBP6 fusion protein Ag2484 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name retinoblastoma binding protein 6
Synonyms p53-associated cellular protein of testis, P2PR, P2P R, MY038, EC:2.3.2.27
Calculated Molecular Weight 1792 aa, 200 kDa
Observed Molecular Weight250 kDa
GenBank Accession NumberBC029352
Gene Symbol RBBP6
Gene ID (NCBI) 5930
RRIDAB_2177794
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ7Z6E9
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RBBP6 (retinoblastoma binding protein 6) is a multifunctional protein that interacts with both p53 and pRb and has been implicated in mRNA processing. It has also been identified as a putative E3 ubiquitin ligase due to the presence of a RING finger domain [PMID:18851979]. RBBP6 contains an N-terminal ubiquitin-like domain and a cysteine-rich RING finger-like domain, through which it promotes the ubiquitination of p53 by Hdm2 in an E4-like manner [PMID:17470788]. It is implicated in a diverse set of cellular functions, including mRNA metabolism, regulation of the cell cycle, tumorigenesis, and development [PMID:12938151,17470788].