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验证数据展示

  • WB analysis using 11882-1-AP (same clone as 11882-1-PBS)

    WB analysis using 11882-1-AP (same clone as 11882-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11882-1-AP (RBBP6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11882-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 11882-1-AP (same clone as 11882-1-PBS)

    IHC staining of human placenta using 11882-1-AP (same clone as 11882-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11882-1-AP (RBBP6 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11882-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RBBP6 antibody included
  • IHC staining of human rectal cancer using 11882-1-AP (same clone as 11882-1-PBS)

    IHC staining of human rectal cancer using 11882-1-AP (same clone as 11882-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human rectal cancer tissue slide using 11882-1-AP (RBBP6 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11882-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RBBP6 antibody included
  • IHC staining of mouse kidney using 11882-1-AP (same clone as 11882-1-PBS)

    IHC staining of mouse kidney using 11882-1-AP (same clone as 11882-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 11882-1-AP (RBBP6 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11882-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RBBP6 antibody included
  • Featured Product
  • KD/KO验证

RBBP6 Polyclonal antibody, PBS Only

RBBP6 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11882-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

p53-associated cellular protein of testis, P2PR, P2P R, MY038, EC:2.3.2.27

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy RBBP6 Ready-To-Use IHC Kit. RBBP6 primary antibody included.

产品信息

11882-1-PBS targets RBBP6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 RBBP6 fusion protein Ag2484 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 retinoblastoma binding protein 6
别名 p53-associated cellular protein of testis, P2PR, P2P R, MY038, EC:2.3.2.27
计算分子量 1792 aa, 200 kDa
观测分子量250 kDa
GenBank蛋白编号BC029352
基因名称 RBBP6
Gene ID (NCBI) 5930
RRIDAB_2177794
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ7Z6E9
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RBBP6 (retinoblastoma binding protein 6) is a multifunctional protein that interacts with both p53 and pRb and has been implicated in mRNA processing. It has also been identified as a putative E3 ubiquitin ligase due to the presence of a RING finger domain [PMID:18851979]. RBBP6 contains an N-terminal ubiquitin-like domain and a cysteine-rich RING finger-like domain, through which it promotes the ubiquitination of p53 by Hdm2 in an E4-like manner [PMID:17470788]. It is implicated in a diverse set of cellular functions, including mRNA metabolism, regulation of the cell cycle, tumorigenesis, and development [PMID:12938151,17470788].