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验证数据展示

  • WB analysis using 84496-4-RR (same clone as 84496-4-PBS)

    WB analysis using 84496-4-RR (same clone as 84496-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84496-4-RR (RBP4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84496-4-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01338-2

    Cytometric bead array standard curve of MP01338-2

    Cytometric bead array standard curve of MP01338-2, RBP4 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84496-1-PBS. Detection antibody: 84496-4-PBS. Standard: Eg31642. Range: 0.156-20 ng/mL.

  • Affinity and Kinetic Characterization of 84496-4-RR

    Affinity and Kinetic Characterization of 84496-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84496-4-RR against Human RBP4 were performed. The affinity constant is 32.4 nM.

RBP4 Recombinant antibody, PBS Only (Detector)

RBP4 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 84496-4-PBS

产品说明书

CloneNo. 241944H4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Cytometric bead array, Indirect ELISA

别名

Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176), Plasma retinol-binding protein, Plasma retinol binding protein

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy RBP4 Ready-To-Use IHC Kit. RBP4 primary antibody included.

产品信息

84496-4-PBS targets RBP4 as part of a matched antibody pair:

MP01338-2: 84496-1-PBS capture and 84496-4-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 retinol binding protein 4, plasma
别名 Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176), Plasma retinol-binding protein, Plasma retinol binding protein
计算分子量 201 aa, 23 kDa
观测分子量 23 kDa
GenBank蛋白编号BC020633
基因名称 RBP4
Gene ID (NCBI) 5950
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP02753
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RBP4 (retinol-binding protein 4) is a carrier protein that transports vitamin A (retinol) from the liver to the peripheral tissues. Synthesized primarily by hepatocytes and adipocytes as a 21 kDa non-glycosylated protein, RBP4 is secreted into the circulation as a retinol-RBP4 complex. In plasma the RBP4-retinol complex is bound to transthyretin (TRR), which prevents prevent kidney filtration. Two truncated forms of RBP4, RBP4-L (truncated at Leu-183) and RBP4-LL (truncated at Leu-182 and Leu-183), exist by proteolytic process. RBP4-L and RBP4-LL, which do not bind TTR, are normally excreted into the urine but accumulate in the serum during renal failure. Urinary RBP4 has been reported as marker for glomerular disease. RBP4 also was identified as an adipokine that elevated in some INS-resistant states. Measurement of serum RBP4 could be used to assess the risk of INS resistance, type 2 diabetes, obesity, and cardiovascular disease. (18752671, 16034410)