RCAS1 Monoclonal antibody
RCAS1 Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat
Applications
ELISA and More (2)
Conjugate
Unconjugated
CloneNo.
4H8A12
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy RCAS1 Ready-To-Use IHC Kit. RCAS1 primary antibody included.
Planning an IF experiment? We recommend our CoraLite® Plus 488 and CoraLite®594 conjugated versions of this antibody.
发表文章中的应用
| WB | See 1 publications below |
| IF | See 1 publications below |
产品信息
66170-1-Ig targets RCAS1 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA Application Description |
| Cited Applications | WB, IF |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | mouse |
| Immunogen | RCAS1 fusion protein Ag2905 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | estrogen receptor binding site associated, antigen, 9 |
| Synonyms | EBAG9, Estrogen receptor-binding fragment-associated gene 9 protein, EBAG 9, EB9, Cancer-associated surface antigen RCAS1 |
| Calculated Molecular Weight | 213 aa, 24 kDa |
| Observed Molecular Weight | 34 kDa |
| GenBank Accession Number | BC017729 |
| Gene Symbol | RCAS1 |
| Gene ID (NCBI) | 9166 |
| RRID | AB_2881565 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | O00559 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Estrogen receptor-binding fragment-associated antigen 9 (EBAG9) gene was identified as an estrogen-responsive gene. The gene product, receptor-binding cancer antigen expressed on SiSo cells (RCAS1), is associated with aggressive characteristics and poor overall survival for 15 different human malignancies. The correlation between RCAS1 expression and several clinicopathological variables, including tumor size, clinical stage, invasion depth and lymph node metastasis highlights this molecule's clinical significance. Expression of RCAS1 in tumor cells plays an important role in evasion from host immune system resulting tumor progression, invasion and metastasis. Further exploration of RCAS1 biological function will facilitate development of novel therapeutic strategies that target RCAS1.
发表文章
| Species | Application | Title |
|---|---|---|
Mol Med Rep RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation |