验证数据展示
产品信息
85024-6-PBS targets RECQL in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | RECQL fusion protein Ag6834 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | RecQ protein-like (DNA helicase Q1-like) |
| 别名 | DNA helicase, RecQ like type 1, DNA dependent ATPase Q1, DNA 3'-5' helicase Q1, ATP-dependent DNA helicase Q1, ATP dependent DNA helicase Q1 |
| 计算分子量 | 73 kDa |
| GenBank蛋白编号 | BC001052 |
| 基因名称 | RECQL |
| Gene ID (NCBI) | 5965 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P46063 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RECQL, also known as RecQ-like helicase, is a member of the RecQ DNA helicase family. These enzymes play a crucial role in maintaining genomic integrity by participating in various DNA repair processes, including mismatch repair, nucleotide excision repair, and direct repair. It's reported that the low RECQL expression is strongly associated with poor prognosis in breast cancer. RECQL expression may be a useful marker in estimating the prognosis of breast cancer patients. (PMID: 29914420)