• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

RENALASE Monoclonal antibody, PBS Only

RENALASE Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3A12F5

Cat no : 60128-1-PBS

Print datasheet

Synonyms

C10orf59, 3A12F5, Monoamine oxidase C, MAO-C, MAO C

验证数据展示

  • WB analysis using 60128-1-Ig (same clone as 60128-1-PBS)

    WB analysis using 60128-1-Ig (same clone as 60128-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60128-1-Ig (RENALASE antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60128-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 60128-1-Ig (same clone as 60128-1-PBS)

    IHC staining of human kidney using 60128-1-Ig (same clone as 60128-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney slide using 60128-1-Ig (RENALASE Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 60128-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 60128-1-Ig (same clone as 60128-1-PBS)

    IHC staining of human kidney using 60128-1-Ig (same clone as 60128-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney slide using 60128-1-Ig (RENALASE Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 60128-1-PBS in a different storage buffer formulation.

  • WB analysis using 60128-1-Ig (same clone as 60128-1-PBS)

    WB analysis using 60128-1-Ig (same clone as 60128-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60128-1-Ig (RENALASE antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60128-1-PBS in a different storage buffer formulation.

产品信息

60128-1-PBS targets RENALASE in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen RENALASE fusion protein Ag13061 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name chromosome 10 open reading frame 59
Synonyms C10orf59, 3A12F5, Monoamine oxidase C, MAO-C, MAO C
Calculated Molecular Weight 38 kDa
Observed Molecular Weight 38 kDa
GenBank Accession NumberBC005364
Gene Symbol RENALASE
Gene ID (NCBI) 55328
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ5VYX0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RNLS, also named as Renalase, C10orf59 and MAO-C, belongs to the renalase family. It is probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. RNLS degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. RNLS has physiologically relevant catecholamine-oxidizing activity. (PMID:15841207 ) This antibody is specific to RNLS.