验证数据展示
产品信息
66441-1-PBS targets RGS4 in WB, Indirect ELISA applications and shows reactivity with human, rat, mouse, pig samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, rat, mouse, pig |
免疫原 | RGS4 fusion protein Ag6029 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | regulator of G-protein signaling 4 |
别名 | RGP4, RGS4, SCZD9 |
计算分子量 | 23 kDa |
观测分子量 | 34 kDa |
GenBank蛋白编号 | BC051869 |
基因名称 | RGS4 |
Gene ID (NCBI) | 5999 |
RRID | AB_2881811 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P49798 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Regulator of G protein signaling (RGS) proteins are a large family of highly diverse, multifunctional signaling proteins. RGS4 is one of seven members of a classic R4 RGS protein that accelerates the GTPase activity of the Gai/o and Gaq/11 family members. RGS4 is highly expressed in multiple brain regions including the cerebral cortex, amygdala, hippocampus, and striatum. Extensive studies have demonstrated that RGS4 plays an important role in regulating smooth muscle contraction, cardiomyocyte development, neural plasticity and psychiatric disorders.