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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 67976-1-Ig (same clone as 67976-1-PBS)

    WB analysis using 67976-1-Ig (same clone as 67976-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67976-1-Ig (RNASEH2A antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67976-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin cancer using 67976-1-Ig (same clone as 67976-1-PBS)

    IHC staining of human skin cancer using 67976-1-Ig (same clone as 67976-1-PBS)

    Immunohistochemical analysis of paraffin-embedded skin cancer slide using 67976-1-Ig (RNASEH2A antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67976-1-PBS in a different storage buffer formulation.

RNASEH2A Monoclonal antibody, PBS Only

RNASEH2A Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67976-1-PBS

产品说明书

CloneNo. 1A2E8

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

ribonuclease H2, subunit A, Ribonuclease H2 subunit A, JUNB, EC:3.1.26.4, Aicardi-Goutieres syndrome 4 protein

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67976-1-PBS targets RNASEH2A in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 RNASEH2A fusion protein Ag9256 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 ribonuclease H2, subunit A
别名 ribonuclease H2, subunit A, Ribonuclease H2 subunit A, JUNB, EC:3.1.26.4, Aicardi-Goutieres syndrome 4 protein
计算分子量 299 aa, 33 kDa
GenBank蛋白编号BC011748
基因名称 RNASEH2A
Gene ID (NCBI) 10535
RRIDAB_2918725
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO75792
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RNASEH2A(Ribonuclease H2 subunit A) is also named as RNASEHI, RNHIA and belongs to the RNase HII family and Eukaryotic subfamily. It is involved in the removal of the initiator RNA primers of Okazaki fragments, an essential step during chromosomal DNA replication of the lagging strand(PMID:9482870). It is an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Defects in RNASEH2A are the cause of Aicardi-Goutieres syndrome type 4 (AGS4).