验证数据展示
产品信息
13753-1-PBS targets RNASET2 in IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | IHC, IF/ICC, IP, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | RNASET2 fusion protein Ag4695 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | ribonuclease T2 |
Synonyms | RNase T2, RNASE6PL, Ribonuclease T2, Ribonuclease 6, EC:4.6.1.19 |
Calculated Molecular Weight | 256 aa, 29 kDa |
Observed Molecular Weight | 29 kDa |
GenBank Accession Number | BC039713 |
Gene Symbol | RNase T2 |
Gene ID (NCBI) | 8635 |
RRID | AB_2285339 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | O00584 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RNASET2(Ribonuclease T2) is also named as RNASE6PL(Ribonuclease 6) and belongs to the RNase T2 family. It is a unique member of the growing family of tumor-antagonizing genes and behaves as a class II tumor suppressor and abolish the tumorigenic potential of an ovarian cancer-derived cell line. This protein has 2 isoforms produced by alternative splicing. Both mildly glycosylated (ranging from38 to 45 kDa) and highly glycosylated forms (ranging from 50 to 80 kDa) of human tumor suppressor protein RNASET2 can be detected in immunoblotting in P. Pastoris(PMID: 21446958).