验证数据展示
产品信息
15297-1-PBS targets RPH3AL in WB, IP, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IP, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | RPH3AL fusion protein Ag7552 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | rabphilin 3A-like (without C2 domains) |
别名 | |
计算分子量 | 34 kDa |
观测分子量 | 38 kDa |
GenBank蛋白编号 | BC005153 |
基因名称 | RPH3AL |
Gene ID (NCBI) | 9501 |
RRID | AB_2181270 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9UNE2 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Rabphilin-3A-like (RPH3AL), also known as Noc2, is a Rab effector protein with a molecular weight of 38 kDa. It is expressed abundantly in endocrine cells but at low levels in exocrine tissues, playing a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells, and also having a key role in INS secretion by pancreatic cells. RPH3AL functions as a potential RAB3B effector protein in epithelial cells, and RPH3AL gene is likely a tumor suppressor.