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验证数据展示

  • WB analysis of rat retina using 24430-1-AP (same clone as 24430-1-PBS)

    WB analysis of rat retina using 24430-1-AP (same clone as 24430-1-PBS)

    rat retina tissue were subjected to SDS PAGE followed by western blot with 24430-1-AP (RS1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24430-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    WB analysis of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    mouse eye tissue were subjected to SDS PAGE followed by western blot with 24430-1-AP (RS1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24430-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    IHC staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 24430-1-AP (RS1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24430-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    IHC staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 24430-1-AP (RS1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24430-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    IF Staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse eye tissue using RS1 antibody (24430-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 24430-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    IF Staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse eye tissue using RS1 antibody (24430-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 24430-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    IF Staining of mouse eye using 24430-1-AP (same clone as 24430-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed frozen OCT-embedded mouse eye tissue using 24430-1-AP (RS1 antibody) at dilution of 1:200 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 24430-1-PBS in a different storage buffer formulation.

RS1 Polyclonal antibody, PBS Only

RS1 Polyclonal Antibody for WB, IHC, IF-P, IF-Fro, Indirect ELISA
Cat No. 24430-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF-P, IF-Fro, Indirect ELISA

别名

XLRS1, Retinoschisin, retinoschisin 1, X linked juvenile retinoschisis protein, X-linked juvenile retinoschisis protein

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

24430-1-PBS targets RS1 in WB, IHC, IF-P, IF-Fro, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF-P, IF-Fro, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 RS1 fusion protein Ag18885 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 retinoschisin 1
别名 XLRS1, Retinoschisin, retinoschisin 1, X linked juvenile retinoschisis protein, X-linked juvenile retinoschisis protein
计算分子量 26 kDa
观测分子量 26 kDa
GenBank蛋白编号BC141638
基因名称 RS1
Gene ID (NCBI) 6247
RRIDAB_2879545
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO15537
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RS1 is also named as XLRS1. RS1 can bind negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides. RS1 is required for normal structure and function of the retina (PMID:19093009). It may play a role in cell-cell adhesion processes in the retina (PMID:27114531). RS1 is high expression in the retina (at protein level) (PMID:10915776, PMID:9326935). It is detected in the inner segment of the photoreceptors, the inner nuclear layer, the inner plexiform layer and the ganglion cell layer. At the macula, it is expressed in both the outer and inner nuclear layers and in the inner plexiform layer (PMID:10915776, PMID:10915776). And RS1 is undetectable in the inner plexiform layers and the inner nuclear layer (PMID:10915776)