验证数据展示
产品信息
67086-1-PBS targets RUNX1T1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
Tested Applications | WB, IHC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat, pig |
Immunogen | RUNX1T1 fusion protein Ag7893 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
Synonyms | Eight twenty one protein, Cyclin-D-related protein, CDR, CBFA2T1, AML1T1 |
Calculated Molecular Weight | 68 kDa |
Observed Molecular Weight | 70-75 kDa |
GenBank Accession Number | BC005850 |
Gene Symbol | RUNX1T1 |
Gene ID (NCBI) | 862 |
RRID | AB_2882394 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q06455 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. Various transcript of the fusion gene has been reported. RUNX1T1 exists some isoforms with MV 68, 67,64, 48 and 44 kDa. The calcualted molecular weight of RUNX1T1 is 67 kDa, but modified RUNX1T1is about 70-75 kDa.