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RUNX2 Recombinant antibody, PBS Only

RUNX2 Uni-rAbTM Recombinant Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

WB, IP, ELISA

Conjugate

Unconjugated

CloneNo.

1G5

Cat no : 82636-2-PBS

Print datasheet

Synonyms

AML3, CBF alpha 1, CBFA1, CCD, CCD1, Oncogene AML 3, OSF 2, OSF2, PEA2 alpha A, PEA2aA, PEBP2 alpha A, PEBP2A, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1, RUNX2

验证数据展示

  • WB analysis using 82636-2-RR (same clone as 82636-2-PBS)

    WB analysis using 82636-2-RR (same clone as 82636-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82636-2-RR (RUNX2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82636-2-PBS in a different storage buffer formulation.

  • IP experiment of ROS1728 using 82636-2-RR (same clone as 82636-2-PBS)

    IP experiment of ROS1728 using 82636-2-RR (same clone as 82636-2-PBS)

    IP result of anti-RUNX2 (IP:82636-2-RR, 4ug; Detection:82636-2-RR 1:500) with ROS1728 cells lysate 2080 ug. This data was developed using the same antibody clone with 82636-2-PBS in a different storage buffer formulation.

82636-2-RR

产品信息

82636-2-PBS targets RUNX2 in WB, IP, ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications WB, IP, ELISA Application Description
Tested Reactivity Human, mouse
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name runt-related transcription factor 2
Synonyms AML3, CBF alpha 1, CBFA1, CCD, CCD1, Oncogene AML 3, OSF 2, OSF2, PEA2 alpha A, PEA2aA, PEBP2 alpha A, PEBP2A, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1, RUNX2
Calculated Molecular Weight 57 kDa
Observed Molecular Weight57-60 kDa
GenBank Accession NumberNM_004348
Gene Symbol RUNX2
Gene ID (NCBI) 860
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ13950
Storage Buffer PBS only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RUNX2, also named as AML3, CBFA1, OSF2 and PEBP2A, is a Transcription factor which involved in osteoblastic differentiation and skeletal morphogenesis. It is essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters By similarity. RUNX2 inhibits MYST4-dependent transcriptional activation.